Georgios Ioannides joined the Foreign Service of the Republic of Cyprus in October 2001. Prior to joining the Foreign Service, between 1996-1998 and 2000-2001, worked at Research Centers and Non-Governmental Organizations, focusing on human rights, European Union affairs and environmental issues. Between 2011-2004 he joined the Ministry of Foreign Affairs, Cyprus Question Directorate and was responsible for issues relating to human rights, enclaved Greek Cypriots, missing persons, cultural heritage and relations with the Turkish Cypriot community.
From 2004-2009 he served a Deputy to the Permanent Representative of the Republic of Cyprus to the Council of Europe, Strasbourg, France where he dealt with issues relating to the European Court of Human Rights, as well as social, education and cultural issues.
He later served in the Ministry of Foreign Affairs, before he was promoted to First Counsellor in October 2014 followed by achieving permanent representation of the Republic of Cyprus to the European Union (2014-2015 Relex Counselor, 2016-2018 Head of the Team for relations with the European Parliament).
In 2023 he was promoted to Minister Plenipotentiary and Extraordinary.